GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THCA | cis | rs7267979 | 1 | rs6107033 | chr20:25363591 | NINL | chr20:25433338-25566153:- | 0.33 | 6.83 | 2.55E-11 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6107033 | chr20:25363591 | PYGB | chr20:25228706-25278647:+ | 0.16 | 4.03 | 6.43E-5 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6107045 | chr20:25441936 | ENTPD6 | chr20:25176339-25207360:+ | -0.31 | -7.06 | 5.79E-12 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6107045 | chr20:25441936 | FAM182A | chr20:26035250-26067552:+ | -0.19 | -3.49 | 0.000526 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6107045 | chr20:25441936 | FAM182B | chr20:25744102-25848786:- | 0.24 | 4.99 | 8.32E-7 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6107045 | chr20:25441936 | NINL | chr20:25433338-25566153:- | -0.37 | -7.51 | 2.94E-13 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6107045 | chr20:25441936 | PYGB | chr20:25228706-25278647:+ | -0.13 | -3.36 | 0.00084 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6107046 | chr20:25442049 | ENTPD6 | chr20:25176339-25207360:+ | -0.31 | -7.06 | 5.79E-12 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6107046 | chr20:25442049 | FAM182A | chr20:26035250-26067552:+ | -0.19 | -3.49 | 0.000526 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6107046 | chr20:25442049 | FAM182B | chr20:25744102-25848786:- | 0.24 | 4.99 | 8.32E-7 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6107046 | chr20:25442049 | NINL | chr20:25433338-25566153:- | -0.37 | -7.51 | 2.94E-13 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6107046 | chr20:25442049 | PYGB | chr20:25228706-25278647:+ | -0.13 | -3.36 | 0.00084 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6107047 | chr20:25442097 | ENTPD6 | chr20:25176339-25207360:+ | -0.31 | -7.06 | 5.79E-12 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6107047 | chr20:25442097 | FAM182A | chr20:26035250-26067552:+ | -0.19 | -3.49 | 0.000526 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6107047 | chr20:25442097 | FAM182B | chr20:25744102-25848786:- | 0.24 | 4.99 | 8.32E-7 | Liver enzyme levels (alkaline phosphatase) |